Figure 2: Structural comparison of ANG and ALS/PD-associated variants. | Scientific Reports

Figure 2: Structural comparison of ANG and ALS/PD-associated variants.

From: Structural insights into human angiogenin variants implicated in Parkinson’s disease and Amyotrophic Lateral Sclerosis

Figure 2

Superposition of native ANG (in green) and ANG-ALS/PD variants (in orange). Residues that exhibit hydrogen bonding or Van der Waals contacts with the ANG-ALS/PD residues in either native ANG or mutant structures are also shown. The variant residues are underlined. The cysteine from the glutathione bound to R121C variant is also shown.

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