Figure 6: Representative micrographs of HE-stained kidneys of S. globosa-infected mice. | Scientific Reports

Figure 6: Representative micrographs of HE-stained kidneys of S. globosa-infected mice.

From: Recombinant Phage Elicits Protective Immune Response against Systemic S. globosa Infection in Mouse Model

Figure 6

Kidneys were removed from mice given intraperitoneal injections of PBS (100 μl/mouse), recombinant phage (25 μg/mouse), heat-killed S. globosa (108 yeast cells/mouse), or wild-type phage (25 μg/mouse) four times at weekly intervals, and then intravenously infected with 2 × 107 S. globosa yeast cells. (A) Kidney from a mouse injected with PBS. Magnification, 200 × . (B) Kidney from a mouse immunized with wild-type phage. Magnification, 200 × . (C) Kidney from a mouse immunized with heat-killed S. globosa (HK-SG). Magnification, 200 × . (D) Kidney from a mouse immunized with recombinant phage. Magnification, 200 × . Photomicrographs (A) and (B) exhibited show a greater number of inflammatory cells in kidneys than group HK-SG (C) and group RP (D). The arrows indicate infiltration of inflammatory cells.

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