Figure 4: Filamentous ABCG1 is disrupted by the actin polymerization blocking agent, Latrunculin B.
From: The ATP binding cassette transporter, ABCG1, localizes to cortical actin filaments
ABCG1 and actin localisation in control (a) and Latrunculin B treated cells (b). White dashed lines show the regions in which ABCG1 organizes in heterogeneous clusters, while yellow lines delimit areas of cell exhibiting more structured, comb-like ABCG1 organization. (c) The variances of the ACF of the Latrunculin B cells were lower than control cells, indicating a loss of ABCG1 and actin association. (d) 2D Kurtosis displays higher peakedness in the Latrunculin B image than in the control image *P < 0.05.
