Figure 1: Analysis of GPR155 expression and identification of candidate molecules that interact with GPR155: assays used indicate downstream effects. | Scientific Reports

Figure 1: Analysis of GPR155 expression and identification of candidate molecules that interact with GPR155: assays used indicate downstream effects.

From: GPR155 Serves as a Predictive Biomarker for Hematogenous Metastasis in Patients with Gastric Cancer

Figure 1

(A) Reduced expression of GPR155 mRNA was detected in all GC cell lines compared with that of FHs74Int. Copy number loss was detected in AGS and SC-6-JCK cells. Methylation of the promoter region of GPR155 was not detected. (B) PCR array analysis showing that the expression level of GPR155 mRNA inversely correlated with those of TWIST1 and WNT5B mRNAs. (C) Cell signaling pathway analysis of AGS cells indicated that inhibition of GPR155 mRNA increased the levels of p-ERK1/2 and p-STAT1.

Back to article page