Figure 3: Measurements of aqueous solutions with different glucose concentrations and different R1 and R2 to confirm the proposed contrasts’ independence of absolute relaxation rates and linearity in the glucose concentration.
From: Fast and Quantitative T1ρ-weighted Dynamic Glucose Enhanced MRI
(a) Measured T1ρ relaxation curves for glucose concentrations of 20 mM and 40 mM and different relaxation rates adjusted using Agar and gadoteric acid (“Agar phantoms”) and Manganese dichloride (“MnCl2 phantoms”). (b) Signal difference ΔS between the measured relaxation curves for 20 mM and 40 mM as a function of TSL for the Agar and MnCl2 phantoms, respectively. (c) ΔSrel obtained for constant TSL = 100 ms as function of the glucose concentration change ΔcGlc for the Agar and MnCl2 phantoms, respectively. The consistency of both curves is in agreement with our simulations (cf. Fig. 2c) and proves the independence of the contrast on absolute relaxations rates.
