Figure 3: USPIO-based MRI quantification.

Signal loss from iron was quantified by measuring the number of black voxels in whole tumor volumes. Mean values with standard deviation are shown for each time point. The asterisk denotes a significantly higher number of black voxels (*p < 0.05; t-test) were detected at 3 weeks (n = 7) compared to 4 days (n = 4).