Figure 4

Pan-caner hierarchical clustering of non-synonymous (A) and synonymous (B) somatic mutation occurrence on protein functional site region. Figure shows cancer SNV occurrence at PTM site vs somatic SNV occurrence at a neighboring region for different cancer types. Color indicates fold of change of somatic SNV occurrence. Red color indicates overrepresentation while blue indicates under-representation. Grey color means that there is no detected somatic SNV on corresponding PTM type for corresponding cancer.