Table 2 pfsSNVs based * summary of the previous and current datasets.

From: Distribution bias analysis of germline and somatic single-nucleotide variations that impact protein functional site and neighboring amino acids

 

Previous Version of Dataset

Current Version of Dataset

%Increase

Somatic Mutation

Germline Mutation

Total

Somatic Mutation

Germline Mutation

Total

Increases by

Acetylation

512

351

863

691

432

1,123

30.1%

Ubiquitination

1,214

841

2055

1562

1052

2,614

27.2%

Phosphorylation

5,466

3917

9383

7373

5282

12,655

34.9%

N-linked glycosylation sites

2,375

1,997

4,372

3,217

2,630

5,847

33.7%

O-linked glycosylation

97

108

205

126

115

241

17.6%

Methylation

163

61

224

208

74

282

25.9%

Crotonylation

42

10

52

57

22

79

52.0%

Nitrosylation

32

43

75

51

48

99

32.0%

Active sites

1,574

811

2385

2,084

1,040

3,124

31.0%

Binding sites

12,286

6,395

18,681

16,630

8,444

25,074

34.2%

Total

23,761

14,534

38,295

31,999

19,139

51,138

33.5%

  1. *Statistics summarized in Table 2 is pfsSNVs based where different functional types occupying the amino acid position are counted separately.
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