Table 2 Spearman rank correlation between variables and baseline biomarker levels in patients with necrotising soft tissue infection.

From: Association between cytokine response, the LRINEC score and outcome in patients with necrotising soft tissue infection: a multicentre, prospective study

 

IL-1β

IL-6

IL-10

TNF-α

Rho

P

Rho

P

Rho

P

Rho

P

LRINEC

0.12

0.14

0.10

0.24

0.09

0.29

0.05

0.55

SAPS II

0.30

0.001

0.41

<0.0001

0.34

<0.0001

0.33

<0.0001

SOFA score

0.34

<0.0001

0.51

<0.0001

0.42

<0.0001

0.44

<0.0001

Leucocyte count

−0.02

0.81

−0.08

0.31

−0.05

0.57

−0.13

0.11

CRP

0.18

0.03

0.17

0.05

0.04

0.67

0.09

0.29

Creatinine

0.34

<0.0001

0.47

<0.0001

0.37

<0.0001

0.38

<0.0001

Lactate

0.58

<0.0001

0.70

<0.0001

0.58

<0.0001

0.64

<0.0001

  1. LRINEC, laboratory risk indicator for necrotising fasciitis; SAPS II, simplified acute physiology score II; SOFA, sequential organ failure assessment; CRP, c-reactive protein.