Table 1 Clinical characteristics of Italian lung adenocarcinoma patients (cases) and healthy controls.
Characteristic | Cases (n = 823) | Controls (n = 779) | Case-control comparison Pa | Association with overall survival b | |
|---|---|---|---|---|---|
HR (95% CI) | P | ||||
Age, years, median (range) | 64 (29–84) | 61 (32–78) | 3.9 × 10−8 | 1.0 (1.0–1.0) | 0.06 |
Sex, n | 0.33 | ||||
Female | 254 | 223 | 1.0 | ||
Male | 569 | 556 | 1.6 (1.2–2.1) | 1.2 × 10−3 | |
Smoking habit, n | <2.2 × 10−16 | ||||
Never | 116 | 15 | 1.0 | ||
Ever | 689 | 758 | 1.1 (0.8–1.6) | 0.58 | |
Missing data | 18 | 6 | |||
Pathological stage, n c | NA | ||||
I | 410 | NA | 1.0 | ||
II | 137 | NA | 2.9 (2.2–3.9) | 4.3 × 10−12 | |
III or IV | 247 | NA | 4.5 (3.5–5.8) | <2.2 × 10−16 | |
Missing data | 29 | 0 | |||
Cases with follow-up data, n | 800 | NA | NA | ||
Median (range) follow-up of patients alive, months | 60 (10–60) | NA | NA | ||
Dead at the 60-month follow-up, n | 354 | NA | NA | ||
