Table 3 SNPs associated with overall survival of lung adenocarcinoma patients (n = 823) in a multivariable Cox proportional hazard model at P < 0.05.

From: Genetic susceptibility variants for lung cancer: replication study and assessment as expression quantitative trait loci

SNP

Chr.

Position (bp) a

Closest genes

Minor allele

HR (95% CI) b

P

rs9557635

13

101,398,739

NALCN

A

1.17 (1.01–1.36)

0.035

rs4105144

19

40,852,719

CYP2A6

T

1.21 (1.02–1.44)

0.025

rs735482

19

45,408,744

CD3EAP; ERCC1

C

0.78 (0.62–0.98)

0.035

  1. aMap position based on genome assembly GRCh38.p5.
  2. bHazard ratio for additive effects (allele dosage) of the minor allele (genotypes were coded with a numerical value, i.e., 0, 1, or 2, according to the number of minor alleles present) on the risk of dying; Cox’s analysis was adjusted by sex, age, pathological stage (I versus > I), and smoking habit; follow-up until 60 months.
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