Table 3 The significantly different pathways of intestinal microbiota between cattle and buffalo.

From: Comparative study of the gut microbiome potentially related to milk protein in Murrah buffaloes (Bubalus bubalis) and Chinese Holstein cattle

Pathway ID

Reporter score (>0, enriched in buffalo; <0, in cattle)

Number of all KOs in the pathway

Number of detected KOs in the pathway (coverage %)

Pathway annotation

Level 1-Pathway

Map01230

5.773

226

194 (85%)

Biosynthesis of amino acids

Metabolism

Map02040

3.245

37

37 (100%)

Flagellar assembly

Cellular Processes

Map00770

3.221

36

32 (89%)

Pantothenate and CoA biosynthesis

Metabolism

Map00540

3.147

38

36 (95%)

Lipopolysaccharide biosynthesis

Metabolism

Map02020

2.969

428

323 (75%)

Two-component system

Environmental Information

Map02060

2.592

79

67 (85%)

Phosphotransferase system (PTS)

Environmental Information

Map00550

2.522

40

35 (88%)

Peptidoglycan biosynthesis

Metabolism

Map00290

2.517

17

16 (94%)

Valine, leucine and isoleucine biosynthesis

Metabolism

Map00780

2.357

19

17 (89%)

Biotin metabolism

Metabolism

Map00020

2.284

56

46 (82%)

Citrate cycle (TCA cycle)

Metabolism

Map00531

2.062

15

14 (93%)

Glycosaminoglycan degradation

Metabolism

Map00520

2.060

144

113 (78%)

Amino sugar and nucleotide sugar metabolism

Metabolism

Map00500

1.934

101

78 (77%)

Starch and sucrose metabolism

Metabolism

Map00450

1.884

28

25 (89%)

Selenocompound metabolism

Metabolism

Map00511

1.884

18

16 (89%)

Other glycan degradation

Metabolism

Map00030

1.874

75

59 (79%)

Pentose phosphate pathway

Metabolism

Map02030

1.794

26

25 (96%)

Bacterial chemotaxis

Cellular Processes

Map00620

−3.530

90

77 (86%)

Pyruvate metabolism

Metabolism

Map00010

−3.337

93

76 (82%)

Glycolysis/Gluconeogenesis

Metabolism

Map03010

−2.948

143

109 (76%)

Ribosome

Genetic Information

Map00633

−2.674

17

17 (100%)

Nitrotoluene degradation

Metabolism

Map00710

−1.971

36

29 (81%)

Carbon fixation in photosynthetic organisms

Metabolism

  1. Note: A reporter score of >1.6 (90% confidence according to normal distribution) could be used as a detection threshold for significantly different pathways.