Table 2 Univariate and multivariate analyses to identify factors influencing early tumor recurrence in patients with HBV-related hepatocellular carcinoma after liver resection.

From: High expression of AKR1B10 predicts low risk of early tumor recurrence in patients with hepatitis B virus-related hepatocellular carcinoma

 

Univariate analysis

Multivariate analysis

Hazard ratio (95% CI)

P

Hazard ratio (95% CI)

P

Gender (female)

0.906 (0.389–2.110)

0.819

—

—

Age ≥60

0.916 (0.475–1.765)

0.793

—

—

AFP ≥200 ng/ml

0.984 (0.587–1.651)

0.952

—

—

HBV-DNA ≥1000 copies/ml

1.052 (0.568–1.948)

0.872

—

—

Cirrhosis

1.406 (0.667–2.965)

0.371

—

—

Tumor size >5 cm

2.396 (1.271–4.515)

0.007

2.513 (1.304–4.845)

0.006

Tumor number ≥2

1.468 (0.850–2.534)

0.068

1.921 (1.085–3.403)

0.025

Macrovascular invasion

2.680 (1.473–4.877)

0.001

2.824 (1.520–5.249)

0.001

Differentiation degree (poorly)

1.757 (1.057–2.924)

0.030

1.767 (1.054–2.967)

0.031

AKR1B10 expression (high)

0.555 (0.333–0.925)

0.024

0.572 (0.340–0.963)

0.036

  1. Factors with a probability threshold of less than 0.100 in univariate analysis were selected into the multivariate Cox regression model. AFP, alpha-fetoprotein; CI, confidence interval; HBV, hepatitis B virus.
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