Table 3 Univariate and multivariate analyses to identify factors influencing overall survival in patients with HBV-related hepatocellular carcinoma after liver resection.

From: High expression of AKR1B10 predicts low risk of early tumor recurrence in patients with hepatitis B virus-related hepatocellular carcinoma

 

Univariate analysis

Multivariate analysis

Hazard ratio (95% CI)

P

Hazard ratio (95% CI)

P

Gender (female)

0.783 (0.183–3.344)

0.741

—

—

Age ≥60

0.582 (0.174–1.949)

0.380

—

—

AFP ≥200 ng/ml

1.003 (0.454–2.216)

0.995

—

—

HBV-DNA ≥1000 copies/ml

0.581 (0.238–1.423)

0.235

—

—

Cirrhosis

2.283 (0.537–9.701)

0.263

—

—

Tumor size >5 cm

1.621 (0.645–4.076)

0.304

—

—

Tumor number ≥2

1.421 (0.610–3.309)

0.416

—

—

Macrovascular invasion

3.551 (1.579–7.985)

0.002

3.662 (1.630–8.230)

0.002

Differentiation degree (poorly)

1.647 (0.741–3.663)

0.221

—

—

AKR1B10 expression (high)

0.447 (0.202–0.988)

0.047

0.429 (0.193–0.951)

0.037

  1. Factors with a probability threshold of less than 0.100 in univariate analysis were selected into the multivariate Cox regression model. AFP, alpha-fetoprotein; CI, confidence interval; HBV, hepatitis B virus.
Back to article page