Figure 4: Gene expressions of sex differentiation markers on dmrt1-deficient gonad.

Dmrt1 and foxl2 are key transcription factors in testicular and ovarian differentiation, respectively. Cyp19a1a encodes for aromatase which is responsible for estrogen production. Sox9a and Amh are male related genes. Relative mRNA expression of dmrt1, foxl2, cyp19a1a, Sox9a and Amh in dmrt1-deficient gonads at one year of age from one dmrt1-deficient and three wild-type gonads. β-actin was used for calibration.