Figure 2: Effect of RAE1 overexpression in breast cancer cell lines. | Scientific Reports

Figure 2: Effect of RAE1 overexpression in breast cancer cell lines.

From: The mitotic checkpoint regulator RAE1 induces aggressive breast cancer cell phenotypes by mediating epithelial-mesenchymal transition

Figure 2

(a) Western blotting results showing stable overexpression of RAE1 in the MCF7, T47D, and MDA-MB-231 breast cancer cell lines. An anti-DDK antibody was used to detect overexpressed RAE1. Full-length blots are presented in Supplementary Fig. 1. (b–g) A Matrigel invasion assay and migration assay were performed to measure the invasive (b,d,f) and migratory (c,e,g) abilities, respectively, of MCF7, T47D, and MDA-MB-231 cells. *p < 0.05, **p < 0.01, ***p < 0.001.

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