Figure 3: Effect of RAE1 knockdown in breast cancer cell lines. | Scientific Reports

Figure 3: Effect of RAE1 knockdown in breast cancer cell lines.

From: The mitotic checkpoint regulator RAE1 induces aggressive breast cancer cell phenotypes by mediating epithelial-mesenchymal transition

Figure 3

(a) Western blot results showing the stable knockdown of RAE1 in MCF7 and MDA-MB-231 breast cancer cell lines. An anti-RAE1 antibody was used to detect RAE1. Full-length blots are presented in Supplementary Fig. 2. (b–e) A Matrigel invasion assay and migration assay were performed to measure the invasive (b,d) and migratory (c,e) abilities, respectively, of MCF7 and MDA-MB-231 cells. *p < 0.05, **p < 0.01, ***p < 0.001.

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