Figure 6: The micrographs showing the thicknesses of the ONL across the vertical meridian. | Scientific Reports

Figure 6: The micrographs showing the thicknesses of the ONL across the vertical meridian.

From: Experimental Study of the Biological Properties of Human Embryonic Stem Cell–Derived Retinal Progenitor Cells

Figure 6

(A1 to A3) Retinas of Long-Even rats at 4 weeks, 8 weeks, and 12 weeks. The average ONL thicknesses were 44.74 ± 1.31 μm, 44.84 ± 1.92 μm, and 45.82 ± 3.29 μm respectively. (B1 to B3) Retinas of sham-treated rats at 4 weeks, 8 weeks, and 12 weeks. The average ONL thicknesses were 7.72 ± 1.01 μm, 6.71 ± 0.52 μm, 4.22 ± 0.73 μm respectively. (C1 to C3) Retinas of transplanted rats at 4 weeks, 8 weeks, and 12 weeks. The average ONL thicknesses were 28.60 ± 1.84 μm, 23.32 ± 0.84 μm, 19.82 ± 1.18 μm respectively. (D) Statistical analysis of ONL thicknesses in three groups at corresponding time. Data from at least three independent experiments are represented as the mean ± SD. GCL, ganglion cells layer; INL, inner nuclear layer; ONL, outer nuclear layer; SRS, subretinal space. ***P < 0.001 compared with the wild-type group; oooP < 0.001 compared with the sham-treated group. Cell nuclei are shown in blue; transplanted cells are shown in red. Scale bars = 100 μm.

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