Figure 5: Association of the CCTTT repeat length polymorphisms with myofibril degradation in AF tissues.

Representative confocal images show myosin degradation in the atria of seven AF patients (4 non-LL and 3 LL) and two controls (with sinus rhythm [SR]). Relative intensity of MHC in the α-actin-expressing area was quantified as described in the Methods section. Data are expressed as mean ± SE. *P = 0.004, SR versus LL groups. #P = 0.004, non-LL versus LL groups. One-way ANOVA with post hoc Tukey’s tests was applied for two groups and multiple comparisons.