Table 1 Vaccines and animal groups.
vaccine | description | dose | animal group |
|---|---|---|---|
SBV-Gc Amino (DNA) | N terminal 234 residues of SBV Gc in pCI expression vector | 100 μg DNA i.m./mouse | M01 |
SBV-Gc Amino (protein) | N terminal 234 residues of SBV Gc expressed in HEK-293T cells | 20 μg protein s.c./mouse; 50 μg protein/cattle | M02, C01 |
SBV-Gc Amino red | reduced form of SBV-Gc Amino (protein) | 20 μg protein s.c./mouse | M03 |
SBV-Gc Amino E. coli | SBV-Gc Amino expressed in E. coli | 20 μg protein s.c./mouse | M04 |
SBV-Gn-L-Gc | covalently linked ectodomains of SBV Gn and Gc expressed in HEK-293T cells | 20 μg protein s.c./mouse; 50 μg protein s.c./cattle | M05, C02 |
AKA-Gc Amino-SBV-Gc Amino | covalently linked SBV-Gc Amino and AKAV-Gc Amino expressed in HEK-293T cells | 20 μg protein s.c./mouse; 50 μg protein s.c./cattle | M06, C03 |
AKA-Gc Amino | N terminal 234 residues of AKAV Gc expressed in HEK-293T cells | 20 μg protein s.c./mouse | M07 |
pCI-vector | pCI expression vector | 100 μg pCI MEGA (DNA) i.m./mouse | M08 |
unvaccinated | — | 100 μl phosphate-buffered saline s.c./mouse | M09, C04 |
