Table 2 Expression values and methylation status of STXBP6 in lung adenocarcinoma among public data set.

From: Identification of Methylation-Driven, Differentially Expressed STXBP6 as a Novel Biomarker in Lung Adenocarcinoma

Data Type

GSE No. (reference)

Sample Size

Correlation a

Expression Difference (log2) b

P-value for Expression c

Methylation Difference (M value) d

P-value for Methylation e

Expression

 

GSE1918847

110

 

−4.22**

3.72E-20

  
 

GSE767049

56

 

−1.37**

1.40E-13

  
 

GSE3121048

246

 

−3.77**

2.47E-12

  
 

GSE1007250

107

 

−1.52**

1.06E-26

  

Methylation

 

GSE19034

60

   

2.24*

2.48E-03

 

GSE3286644

50

   

2.04**

3.58E-08

Expression & Methylation

 

GSE19804/GSE49996

120/64

−0.52

−4.38**

9.57E-22

1.73**

8.61E-08

 

GSE62949/GSE62948

56/56

−0.60

−0.24**

3.84E-11

1.08**

5.98E-08

 

GSE32863/GSE32861(44)

114/118

−0.68

−1.83**

9.29E-22

2.54**

2.49E-18

 

GSE63459/GSE6338451

62/70

−0.53

−1.79*

4.20E-02

1.34**

2.21E-08

  1. aCorrelation between gene expression and methylation status.
  2. bDifferential median values of gene in tumor/normal tissue samples (log2 ratio).
  3. cStatistical significance of gene expression by t test or paired-t test.
  4. dDifferential median values of methylated probes versus unmethylated probes (M value).
  5. eStatistical significance of methylation examined by paired-t test.
  6. *P < 1.00E-2; **P < 1.00E-07.