Table 2 Relationships between clinicopathological characteristics and pre-treatment NLR.
Characteristics | NLR radio | p value | |
|---|---|---|---|
<5 (n = 313) | ≥5 (n = 204) | ||
Age (years) | 0.278 | ||
<60 | 47 (55.3) | 38 (44.7) | |
≥60 | 266 (61.6) | 166 (38.4) | |
Gender | 0.584 | ||
Male | 249 (61.2) | 158 (38.8) | |
Female | 64 (58.2) | 46 (41.8) | |
Smoking at diagnosis | 0.351 | ||
Never smoker | 194 (59.0) | 135 (41.0) | |
Current or ex-smoker | 119 (63.3) | 69 (36.7) | |
ECOG PS at diagnosis | 0.033 | ||
0–1 | 226 (63.7) | 129 (36.3) | |
≥2 | 87 (53.7) | 75 (46.3) | |
Tumor location | 0.237 | ||
Proximal third | 31 (70.5) | 13 (29.5) | |
Middle third | 225 (58.6) | 159 (41.4) | |
Distal third | 57 (64.0) | 32 (36.0) | |
Tumor length (cm) | <0.001 | ||
<5 | 202 (68.9) | 91 (31.1) | |
≥5 | 111 (49.6) | 113 (50.4) | |
Tumor differentiation | 0.892 | ||
Well | 37 (57.8) | 27 (42.2) | |
Moderate | 217 (61.0) | 139 (39.0) | |
Poor | 59 (60.8) | 38 (39.2) | |
Node stage | 0.158 | ||
N0 | 102 (56.4) | 79 (43.6) | |
N1 | 211 (62.8) | 125 (37.2) | |
Metastasis stage | <0.001 | ||
M0 | 293 (63.7) | 167 (36.3) | |
M1-lym | 20 (35.1) | 37 (64.9) | |
Tumor stage | <0.001 | ||
II | 65 (78.3) | 18 (21.7) | |
III/IV | 248 (57.1) | 186 (42.9) | |
Hemoglobin concentration (g/L) | 0.255 | ||
<120 | 73 (56.2) | 57 (43.8) | |
≥120 | 240 (62.0) | 147 (38.0) | |
SCCA at diagnosis (ng/ml) | 0.365 | ||
<1.5 | 142 (62.8) | 84 (37.2) | |
≥1.5 | 171 (58.8) | 120 (41.2) | |
CEA at diagnosis (ng/ml) | 0.705 | ||
<5 | 207 (61.2) | 131 (38.8) | |
≥5 | 106 (59.2) | 73 (40.8) | |
Adjuvant chemotherapy | 0.496 | ||
Yes | 93 (29.7) | 220 (70.3) | |
No | 67 (32.8) | 137 (67.2) | |
dCRT response | <0.001 | ||
CR + PR | 224 (77.0) | 67 (23.0) | |
SD + PD | 89 (39.4) | 137 (60.6) | |
