Figure 6: Transplantation of OGD-preconditioned microglia promotes expression of remodelling factors at 28 days after cerebral ischemia.
From: Microglia preconditioned by oxygen-glucose deprivation promote functional recovery in ischemic rats
(A–C) Representative figures and the relative signal intensities of vascular endothelial growth factor (VEGF) (A), matrix metalloproteinase-9 (MMP-9) (B), and transforming growth factor-β (TGF-β) (C) from cerebral cortices of the no cell control group and the microglia or astrocyte transplanted groups at 28 days after cerebral ischemia. VEGF (A), MMP-9 (B), and TGF-β (C) (red)/MAP2 (green)/DAPI (blue) triple labelling of cerebral cortices in the border between the ischemic core and penumbra at 28 days after reperfusion as examined by confocal microscopy. A secondary-only antibody control confirms its specificity. Scale bars, 15 μm. Bar graphs represent relative signal intensities of ischemic brain samples compared with those of no cell control samples (N = 21–28). **P < 0.01.
