Table 3 Main Results of Pooled ORs and Analysis of C4,C4A and C4B CNV with Autoimmune Diseases in this Meta-Analysis.

From: Association between C4, C4A, and C4B copy number variations and susceptibility to autoimmune diseases: a meta-analysis

  

<4 VS ≥ 4 C4

 

<2 VS ≥ 2 C4A

 

<2 VS ≥ 2 C4B

 

Classification

N(Case/Control)

OR

95%CI

PH

OR

95%CI

PH

OR

95%CI

PH

All disease

 

1.46

(1.19, 1.78)

<0.001

1.46

(1.10, 1.94)

<0.001

1.07

(0.93, 1.24)

<0.001

 SLE

8(3672/4746)

1.80

(1.51, 2.13)

0.016

2.13

(1.71, 2.64)

0.003

1.18

(0.94, 1.47)

<0.001

 Other

8(4991/6353)

1.05

(0.80, 1.38)

<0.001

0.94

(0.64, 1.38)

<0.001

0.96

(0.80, 1.16)

0.013

 Ethnicity

Asian

7(4992/7380)

1.13

(0.88, 1.45)

<0.001

0.98

(0.65, 1.49)

<0.001

0.96

(0.82, 1.12)

0.021

Caucasian

9(3671/3719)

1.91

(1.42, 2.56)

<0.001

2.05

(1.49, 2.83)

<0.001

1.25

(0.96, 1.63)

<0.001

  1. PH: P value for heterogeneity.
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