Table 3 Performance of the RuralDiab risk score and comparison with previously published risk scores for predicting T2DM in validation population.

From: Development and evaluation of a risk score for type 2 diabetes mellitus among middle-aged Chinese rural population based on the RuralDiab Study

 

Risk variables

AUC

Cutoff value

Number of risk,%

Sensitivity, %

Specificity, %

PPV, %

NPV, %

+LR

−LR

the RuralDiab risk score

Sex, age, family history of diabetes, physical activity, waist circumference, BMI, history of dyslipidemia, DBP

0.723 (0.710–0.735) in total

17

1587 (34.1)

67.9 (61.7–73.6)

67.8 (66.4–69.2)

10.6

97.4

2.11

0.47

  

0.711 (0.688–0.732) in men

18

599 (36.5)

70.2 (60.4–78.8)

65.8 (63.3–68.1)

12.2

97.0

2.05

0.45

  

0.726 (0.709–0.742) in women

16

1088 (36.1)

70.3 (62.2–77.6)

65.6 (63.8–67.3)

9.4

97.8

2.05

0.45

the New Chinese Diabetes Risk Score

Sex, age, family history of diabetes, waist circumference, BMI, systolic blood pressure

0.708 (0.695–0.721) in total

24

2046 (43.97)

75.5 (69.7–80.7)

57.8 (56.3–59.3)

9.2

97.7

1.79

0.42

  

0.686 (0.663–0.709) in men

24

753 (45.9)

74.0 (64.5–82.1)

56.0 (53.5–58.5)

10.2

97.0

1.68

0.46

  

0.720 (0.704–0.736) in women

24

1293 (42.9)

76.6 (68.8–83.2)

58.8 (56.9–60.6)

8.6

98.0

1.86

0.40

the ADA score

Age, delivered a macrosomic (≥9 lb) infant, diabetes in parents or siblings, BMI

0.636 (0.622–0.650)# in total

5

1391 (29.9)

49.8 (43.4–56.2)

71.2 (69.9–72.6)

8.9

96.2

1.73

0.70

  

0.628 (0.604–0.651)# in men

5

390 (23.8)

44.2 (34.5–54.3)

77.6 (75.5–79.7)

11.8

95.4

1.98

0.72

  

0.648 (0.630–0.665)# in women

5

1001 (33.2)

53.8 (45.3–62.1)

67.8 (66.1–69.5)

7.8

96.7

1.67

0.68

the Inter99 score

Sex, age, physical activity, history of diabetes in parent, hypertension, BMI

0.669 (0.655–0.682)# in total

23

1337 (28.7)

53.0 (46.6–59.3)

72.6 (71.3–74.0)

9.9

96.5

1.94

0.65

  

0.618 (0.594–0.642)# in men

23

506 (30.8)

49.0 (39.1–59.0)

70.4 (68.0–72.7)

10.1

95.3

1.66

0.72

  

0.697 (0.680–0.713) in women

18

1185 (39.3)

69.7 (61.5–77.0)

62.2 (60.4–64.0)

8.5

97.6

1.84

0.49

the Thai risk score

Sex, age, diabetes history of parent or sibling, hypertension, BMI, waist circumference

0.709 (0.695–0.722) in total

6

2109 (45.3)

75.5 (69.7–80.7)

56.4 (54.9–57.9)

8.9

97.6

1.73

0.43

  

0.696 (0.673–0.718) in men

7

530 (32.3)

61.5 (51.5–70.9)

69.7 (67.3–72.0)

12.1

96.4

2.03

0.55

  

0.713 (0.696–0.729) in women

6

1342 (44.6)

77.9 (70.3–84.4)

57.1 (55.3–59.0)

8.4

98.1

1.82

0.39

the Oman risk score

Age, family history of diabetes, waist circumference, BMI, hypertension

0.675 (0.662–0.689)# in total

10

1646 (35.4)

61.4 (55.1–67.5)

66.1 (64.7–67.5)

9.3

96.8

1.81

0.58

  

0.659 (0.636–0.682)# in men

7

692 (42.2)

68.3 (58.4–77.0)

59.6 (57.1–62.1)

10.3

96.5

1.69

0.53

  

0.696 (0.679–0.712) in women

10

1284 (42.6)

72.4 (64.4–79.5)

58.8 (56.9–60.6)

8.2

97.7

1.76

0.47

  1. AUC = area under the curve; PPV = positive predictive value; NPV = negative predictive value; +LR = positive likelihood ratio;
  2. −LR = negative likelihood ratio; DBP = diastolic blood pressure; BMI = body mass index; T2DM = type 2 diabetes mellitus.
  3. #compared with the RuralDiab risk score P < 0.05.