Figure 6: Aptamer (H8) binding to RSV and competitive effect of the F-protein selective palivizumab monitored by fluorescence polarization. | Scientific Reports

Figure 6: Aptamer (H8) binding to RSV and competitive effect of the F-protein selective palivizumab monitored by fluorescence polarization.

From: Aptamers for respiratory syncytial virus detection

Figure 6

The 0.5 nM Alexa Fluor 488 labelled H8 aptamer shows a polarization of ca. 50 mP that increases drastically in mixture with RSV indicating their binding. No change in the fluorescence polarization was obtained in the presence of a 100 × excess of F-protein selective antibody with respect of the aptamer.

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