Figure 3: FAM83H-AS1 involved in tumor cell proliferation and invasion. | Scientific Reports

Figure 3: FAM83H-AS1 involved in tumor cell proliferation and invasion.

From: Overexpression of FAM83H-AS1 indicates poor patient survival and knockdown impairs cell proliferation and invasion via MET/EGFR signaling in lung cancer

Figure 3

(A) The knockdown efficiency of FAM83H-AS1 siRNA in PC-9 and H1650 cells measured by qRT-PCR. The FAM83H-AS1 expression decreased more than 70% after FAM83H-AS1 siRNA (10 nM SMARTpool, at 48 h) transfection. (B) Cell proliferation was altered after FAM83H-AS1 siRNAs treatment (96–120 h) in 12 lung cancer cell lines. (C–F) cell invasion and migration decreased after FAM83H-AS1 knockdown by siRNA in both PC-9 and H1650 cell lines (20X) analyzed using Boyden chambers assay. siRNA = FAM83H-AS1 siRNA; NT = non-targeting control siRNA.

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