Table 2 Pairwise linkage disequilibrium (LD) test for seven polymorphic loci of the β-globin cluster in the southwest Chinese ethnic minority population.

From: β-globin gene cluster haplotypes in ethnic minority populations of southwest China

Locus

HincII 5′ε

HindIII G γ

HindIII Aγ

HincII 5′Ψβ

HincII 3′Ψβ

AvaII β

Hinf I 3′ β

HincII 5′ ε

 

−897.986

−856.781

−925.626

−828.596

−1336.707

−1278.332

HindIII G γ

0

 

−909.472

−918.317

−904.678

−1340.644

−1284.383

HindIII Aγ

0

0

 

−878.712

−864.688

−1239.161

−1182.412

HincII 5′ Ψβ

0

0

0

 

−917.026

−1167.372

−1109.937

HincII 3′ Ψβ

0

0

0

0

 

−1345.222

−1288.511

AvaII β

0.231

0.437

0.488

0.802

0.561

 

−1241.530

Hinf I 3′ β

0.004

0.070

0.042

0.028

0.049

0

 
  1. The values above the diagonal are likelihood of LD (LnLHood) obtained by applying the EM algorithm to estimate haplotype frequencies, and the values below the diagonal are corresponding p-values of the likelihood-ratio test (d.f. = 1. Significance p-value = 0.05; number of permutations = 1000). Bold indicates the pairwise linkage equilibrium (p > 0.05 in the linkage disequilibrium test).