Figure 1: Sample-dependence of image-based correction methods.
From: Image-based adaptive optics for in vivo imaging in the hippocampus
Simulated variation of the mean image intensity metric with respect to aberration amplitude with a 10 μm fluorescent bead in focus (A,B) and 12 μm out-of-focus (C,D) for coma (A,C) and spherical aberration (B,D). Insets: schematics of the 2D axial profile (xz) of the point spread function and the fluorescent bead for different aberration amplitudes: −2.1, 0, 2.1 rad of coma (A,C); −2.3, 0, 2.3 rad of spherical aberration (B) and −2.3, 0 rad of spherical aberration (D). The focused beam propagates along the Z axis.
