Figure 1: In silico analyses of hydrophobic patch in NS. | Scientific Reports

Figure 1: In silico analyses of hydrophobic patch in NS.

From: A hydrophobic patch surrounding Trp154 in human neuroserpin controls the helix F dynamics with implications in inhibition and aggregation

Figure 1

(a) Interactions of W154 present on helix F in WT NS. Green residues are involved in hydrophobic interaction while orange residue makes hydrogen bond with W154. (b) Superimposition of native PDB ID: 3FGQ29 (pink) and cleaved NS PDB ID: 3F0230 (blue). The images were generated using Chimera47 and the distance was calculated through the program module.

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