Table 1 Sequences and physicochemical properties of the peptides.

From: Highly potent antimicrobial peptides from N-terminal membrane-binding region of E. coli MreB

Peptide name

Peptide sequence [a]

z [b]

〈H〉[c]

〈μH〉 [c]

D

MreB1–9

MLKKFRGMF-am

+4

0.528

0.762

2.039

Ac-MreB1–9

Ac-MLKKFRGMF-am

+3

0.528

0.762

1.709

W-MreB1–9

WMLKKFRGMF-am

+4

0.7

0.523

1.814

Ac-W-MreB1–9

Ac-WMLKKFRGMF-am

+3

0.7

0.523

1.484

  1. [a]‘Ac-’ at N-terminus represents acetylated amino-terminus, while ‘-am’ at C-terminus represents C-terminal amide.
  2. [b]Net charge on the peptide at pH 7.4
  3. [c]〈H〉 and 〈μH〉 were calculated using Heliquest web server12.
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