Table 3 Antimicrobial activity of the peptides.

From: Highly potent antimicrobial peptides from N-terminal membrane-binding region of E. coli MreB

Microbe

Minimum Lethal Concentration (μM) [a]

MreB1–9

Ac-MreB1–9

W-MreB1–9

Ac-W-MreB1–9

Escherichia coli

20

15

5

10

Pseudomonas aeruginosa

10

100

3

10

Salmonella enterica

10

15

3

2

Staphylococcus aureus

50

100

10

10

Staphylococcus aureus (Gentamicin and Methicillin-resistant)

20

20

5

5

Candida albicans

15

15

5

5

  1. The assays were carried out with the mid-log phase cells in 10 mM phosphate buffer, pH 7.4. [a]Minimum peptide concentration that resulted in complete killing of the bacteria/fungus.