Figure 6: HMGB1 and Sirt1 regulate the induction of MxA in response to IFN-β. | Scientific Reports

Figure 6: HMGB1 and Sirt1 regulate the induction of MxA in response to IFN-β.

From: Resveratrol treatment reveals a novel role for HMGB1 in regulation of the type 1 interferon response in dengue virus infection

Figure 6

HMGB1-knockdown cells (A, shHMGB1) and Sirt1-knockdown cells (C, shSirt1) were stimulated with 50 μM IFN-β for 16 h and the MxA levels were determined using Western blot analysis. Huh7 cells were treated with 80 μM RESV (B, RESV-treated) for 4 h before and during the stimulation of 50 μM IFN-β for 16 h and the MxA levels were determined using Western blot analysis. Band intensities for the ratio of MxA and β-actin were determined by Image J analysis.

Back to article page