Figure 7: Effects of PVN infusion of PD98059 on the PVN TH and GAD67 in salt-induced hypertensive rats. | Scientific Reports

Figure 7: Effects of PVN infusion of PD98059 on the PVN TH and GAD67 in salt-induced hypertensive rats.

From: PVN Blockade of p44/42 MAPK Pathway Attenuates Salt-induced Hypertension through Modulating Neurotransmitters and Attenuating Oxidative Stress

Figure 7

(A) A representative immunoblot. (B) Densitometric analysis of protein expression of TH and GAD67. High-salt diet (HS) rats had higher levels of TH and lower level of GAD67 compared with normal-salt (NS) rats (P < 0.05, n = 7). PVN infusion of PD98059 significantly attenuated expression of TH, and augmented expression of GAD67 in PVN of HS rats compared with control (P < 0.05, n = 7). Values are mean ± SE. *P < 0.05 vs control (NS + PVN aCSF or NS + PVN PD98059); †P < 0.05, HS + PVN PD98059 vs HS + PVN aCSF.

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