Figure 3: Effects of Ac-PGP treatment on the cutaneous wound healing. | Scientific Reports

Figure 3: Effects of Ac-PGP treatment on the cutaneous wound healing.

From: N-Acetylated Proline-Glycine-Proline Accelerates Cutaneous Wound Healing and Neovascularization by Human Endothelial Progenitor Cells

Figure 3

(a) Excisional skin wounds introduced by 8-mm biopsy punch on the dermal skin in rats were treated daily with HBSS or indicated concentration of Ac-PGP. Representative images taken at indicated days after introducing wounds are shown. (b) Quantitative analysis of wound area at the indicated days in comparison with the original wound using Image J software (version 1.50i) is shown. Data indicate mean ± SD. $p < 0.05, $$p < 0.01 0.01 uM Ac-PGP versus 0 uM Ac-PGP; **p < 0.01, ***p < 0.001 0.1 uM Ac-PGP versus 0 uM Ac-PGP; #p < 0.05 1 uM Ac-PGP versus 0 uM Ac-PGP; &p < 0.05 10 uM Ac-PGP versus 0 uM Ac-PGP (n = 12). (c) Representative images of cutaneous wound tissues at the indicated days after H&E staining are shown. Wound gap, the distance between the advancing edges of wounds, is marked by a black line. Bar = 200 μm. (d) Quantitative analysis of the wound gap on the indicated days during recovery the period is shown. The wound gap was measured using the Image J software program (version 1.50i). Data indicate mean ± SD. *p < 0.05, **p < 0.01 versus HBSS (n = 6).

Back to article page