Figure 9: Schematic summarizing the role of fractalkine-CX3CR1 signaling in Norgestrel-mediated retinal neuroprotection.
From: Fractalkine-CX3CR1 signaling is critical for progesterone-mediated neuroprotection in the retina
GI254023X is a potent inhibitor of ADAM10, a metalloproteinase responsible for the cleavage of membrane-bound fractalkine.
