Figure 1: Experimental timeline for azoxymethane (AOM) treatment and voluntary running wheel access. | Scientific Reports

Figure 1: Experimental timeline for azoxymethane (AOM) treatment and voluntary running wheel access.

From: Prevention of tumorigenesis in mice by exercise is dependent on strain background and timing relative to carcinogen exposure

Figure 1

(a) experiment 1 (AOM 1), 45 female mice from each of six strains (CC001/Unc, A/J, C57BL6/J, C58/J, KK/HIJ, I/LNJ). Mice were randomly assigned to one of the two-wheel access groups depicted or a third that never had access to running wheels. (b) experiments 2 and 3 (AOM 2, 3), for AOM 2, 96 (n = 48 males, n = 48 females) mice were utilized from the A/J strain. In AOM 3, 40 female A/J mice were used. Mice were randomly assigned to one of the three-wheel access groups depicted or a fourth that never had access to running wheels. (c) experiment 4 (AOM 4) 20 female A/J mice (n = 10, wheel access; n = 10, no wheel access).

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