Figure 3: Effects of LOS on AT1R and PKCγ expression in the PVN of salt-induced hypertensive rats. | Scientific Reports

Figure 3: Effects of LOS on AT1R and PKCγ expression in the PVN of salt-induced hypertensive rats.

From: Renin-angiotensin system acting on reactive oxygen species in paraventricular nucleus induces sympathetic activation via AT1R/PKCγ/Rac1 pathway in salt-induced hypertension

Figure 3

Expressions of AT1R and PKCγ in high salt intake (HS) rats were higher than in control rats. Treatment with LOS attenuated the AT1R and PKCγ expression in the PVN of HS rats. (A) Immunofluorescence for AT1R (bright green) and immunohistochemistry for PKCγ (bright brown) in the PVN in different groups. (B) and (C) Column diagram showing the numbers of AT1R and PKCγ positive neurous cells in the PVN in different groups. *P < 0.05 vs NS groups (NS + PVN LOS or NS + aCSF); †P < 0.05 HS + LOS vs HS + aCSF.

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