Figure 5
From: Unusual Anti-allergic Diterpenoids from the Marine Sponge Hippospongia lachne
(A) Cytotoxic effects of 1 and 2 on RBL-2H3 cells. (B) Inhibitory effects of 1 and 2 on the release of β-hexosaminidase in DNP-IgE-activated RBL-2H3 cells. (C) Inhibition of IL-4 production of 1 and 2 in RBL-2H3 cells. (D) Inhibitory activity on lipid mediator LTB4 secretion of 1 and 2 in RBL-2H3 cells. Data are presented as the mean ± SD values of triplicate determinations. *P < 0.05, **P < 0.01, ***P < 0.001 versus DNP-BSA-treated group (n = 3). Data are analyzed by one-way ANOVA followed by Tukey’s Multiple Comparison Post-Test (GraphPad Prism 5.0).
