Figure 5: RNAi knockdown of Relish 2 led to reduced expression of AMP genes induced by r-bursicon homodimers or heterodimer.
From: Relish2 mediates bursicon homodimer-induced prophylactic immunity in the mosquito Aedes aegypti
(A) dsRelish 1 treatments led to gene-specific reduction of mRNA encoding Relish 1, but not Relish 2. (B) dsRelish 2 treatment led to gene-specific reduction of mRNA encoding Relish 2, but not Relish 1. Bars annotated with the same letter are not significantly different, P < 0.05. (C) The induction of CecA and DefA by r-bursicon homodimers and heterodimer was attenuated by dsRelish2, but not dsRelish 1. Asterisks indicate significant differences (*P < 0.05; **P < 0.01) from the control group.
