Table 2 Run time of the variant calling process for the eight variant calling tools investigated regarding the first and second dataset.

From: Evaluating Variant Calling Tools for Non-Matched Next-Generation Sequencing Data

Variant caller

Preprocessing

CPU time (first dataset)

CPU time (second dataset)

Option for multithreading

GATK

yes

1,021 min

4,876 min

yes

Platypus

no

59 min

9,952 min

yes

VarScan

yes

649 min

2,906 min

no

LoFreq

yes

945 min

11,991 min

yes

FreeBayes

no

732 min

6,652 min

no

SNVer

no

492 min

14,431 min

no

SAMtools

yes

305 min

1,859 min

no

VarDict

no

281 min

3,513 min

no