Table 5 Sensitivity, specificity and ability of discrimination and calibration for recalibrated the FRS, SCORE, CN-ICVD and PCE models for 5-year cardiovascular mortality.
Models | Cut-off# (%) | Sensitivity (95%CI) | Specificity (95%CI) | +LR* | −LR** | AUC (95%CI) | χ2 | P |
|---|---|---|---|---|---|---|---|---|
general-FRS | ||||||||
Men | 1.16 | 80.00 (69.6–88.1) | 62.23 (60.7, 63.8) | 2.12 | 0.32 | 0.776 (0.763, 0.789) | 4.032 | 0.402 |
Women | 1.14 | 73.86 (63.4–82.7) | 70.93 (69.8–72.0) | 2.54 | 0.37 | 0.756 (0.746, 0.767) | 9.448 | 0.051 |
simplified-FRS | ||||||||
Men | 1.17 | 82.50 (72.4, 90.1) | 62.77 (61.2, 64.3) | 2.22 | 0.28 | 0.795 (0.782, 0.807) | 1.160 | 0.798 |
Women | 0.73 | 87.50 (78.7, 93.6) | 55.03 (53.8, 56.3) | 1.95 | 0.23 | 0.753 (0.742, 0.763) | 24.735 | <0.001 |
SCORE-low | ||||||||
Men | 1.16 | 65.00 (53.5–75.3) | 70.94 (69.5–72.4) | 2.24 | 0.49 | 0.733 (0.719, 0.747) | 22.430 | <0.001 |
Women | 0.2 | 79.07 (69.0, 87.1) | 61.08 (59.8, 62.3) | 2.03 | 0.34 | 0.743 (0.732, 0.754) | 35.675 | <0.001 |
SCORE-high | ||||||||
Men | 1.44 | 78.75 (68.2, 87.1) | 57.21 (55.6–58.8) | 1.84 | 0.37 | 0.731 (0.717, 0.745) | 5.109 | 0.276 |
Women | 0.27 | 79.55 (69.6–87.4) | 60.41 (59.2–61.6) | 2.01 | 0.34 | 0.739 (0.728, 0.749) | 28.819 | <0.001 |
CN-ICVD | ||||||||
Men | 1.03 | 82.50 (72.4, 90.1) | 63.98 (62.4, 65.5) | 2.29 | 0.27 | 0.793 (0.780, 0.805) | 2.917 | 0.405 |
Women | 1.01 | 73.86 (63.4, 82.7) | 68.00 (66.8, 69.2) | 2.31 | 0.38 | 0.755 (0.745, 0.766) | 5.375 | 0.251 |
PCE-white | ||||||||
Men | 1.02 | 85.00 (75.3, 92.0) | 57.90 (56.3, 59.5) | 2.02 | 0.26 | 0.779 (0.766, 0.792) | 12.513 | 0.014 |
Women | 0.99 | 77.27 (67.1–85.5) | 67.05 (65.9, 68.2) | 2.35 | 0.34 | 0.758 (0.747, 0.768) | 4.572 | 0.334 |
PCE-AA | ||||||||
Men | 1.16 | 80.00 (69.6, 88.1) | 62.23 (60.7, 63.8) | 2.12 | 0.32 | 0.776 (0.763, 0.789) | 4.032 | 0.402 |
Women | 1.02 | 73.86 (63.4, 82.7) | 69.36 (68.2, 70.5) | 2.41 | 0.38 | 0.760 (0.750, 0.771) | 10.720 | 0.030 |
