Figure 2: Basal articular cartilage in AMPKα1α2 conditional double knockout (AMPKα cDKO) mice and their Cre-negative wild-type (WT) littermates. | Scientific Reports

Figure 2: Basal articular cartilage in AMPKα1α2 conditional double knockout (AMPKα cDKO) mice and their Cre-negative wild-type (WT) littermates.

From: AMPK deficiency in chondrocytes accelerated the progression of instability-induced and ageing-associated osteoarthritis in adult mice

Figure 2

(a) Safranin-O/Fast green and (b) H&E staining of knee joints from 10-week-old AMPKα cDKO mice and their WT littermates administrated TM at age 8 weeks for 5 days (n = 6/group). Scale bars = 100 μm. Representative IF images of (c) Col2a1 and (d) Sox9 in knee joints from 10-week-old AMPKα cDKO mice and their WT littermates administrated TM at age 8 weeks for 5 days (n = 6/group). Green indicates positive staining. Blue represents DAPI staining. No intensity or background adjustments were made between sections. Col2a1 = Type II collagen. Scale bars = 50 μm.

Back to article page