Figure 7: TUNEL analyses of surgically induced and ageing-associated OA. | Scientific Reports

Figure 7: TUNEL analyses of surgically induced and ageing-associated OA.

From: AMPK deficiency in chondrocytes accelerated the progression of instability-induced and ageing-associated osteoarthritis in adult mice

Figure 7

(a) Representative TUNEL images in the medial tibial plateau in AMPKα1α2 conditional double knockout (AMPKα cDKO) mice and their WT littermates 2 weeks post-sham operation and DMM surgery or in mice at 9 months of age. Green represents positive staining. Blue indicates DAPI staining. No intensity or background adjustments were made between sections. Scale bars = 50 μm. (b) Quantifications of the percentage of TUNEL-positive cells are presented as percentages relative to cells stained for DAPI. (n = 6/group) TUNEL = terminal deoxynucleotidyl transferase dUTP nick end labelling; **p < 0.01. ***p < 0.001. NS = not significant.

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