Table 1 Association between the 21 selected previously reported SNPs and risk of CRC in the study population.

From: Risk Model for Colorectal Cancer in Spanish Population Using Environmental and Genetic Factors: Results from the MCC-Spain study

SNP

Chr

Position

Mapped Gene

Risk Allele

Risk Allele Frequency

Reported p-value

Reported OR

OR MCC-Spain

95% CI

p-value

rs10752881

1

183004356

KRT18P28 - LAMC1

A

0.76

5.0E-06

1.07

1.11

1.01–1.21

0.04

rs6691170

1

221872104

DUSP10 - QRSL1P2

T

0.31

1.0E-09

1.06

1.09

0.99–1.20

0.08

rs10936599

3

169774313

MYNN

C

0.19

3.0E-08

1.04

1.10

0.98–1.23

0.11

rs1321311

6

36655123

N/A

C

0.30

1.0E-10

1.10

1.03

0.93–1.15

0.54

rs7758229

6

160419220

SLC22A3

T

0.67

8.0E-09

1.28

1.07

0.96–1.18

0.21

rs16892766

8

116618444

LINC00536 - EIF3H

C

0.39

3.0E-18

1.27

1.17

0.98–1.39

0.08

rs6983267

8

127401060

CCAT2 - LOC101930033

G

0.82

1.0E-14

1.27

1.10

1.00–1.21

0.04

rs10795668

10

8659256

RNA5SP299 - LINC00709

G

0.73

5.0E-15

1.15

1.06

0.95–1.17

0.30

rs4948317

10

58811675

BICC1

C

0.30

7.0E-08

1.10

1.07

0.97–1.18

0.19

rs3802842

11

111300984

COLCA2 - COLCA1

C

0.08

6.0E-10

1.11

1.09

0.98–1.20

0.12

rs3824999

11

74634505

POLD3

G

0.13

4.0E-10

1.08

1.09

1.00–1.20

0.06

rs10879357

12

72020783

TPH2

G

0.50

3.0E-06

1.25

1.00

0.91–1.11

0.94

rs11169552

12

50761880

DIP2B - ATF1

C

0.82

2.0E-10

1.09

1.02

0.91–1.14

0.80

rs7315438

12

115453598

TBX3 - UBA52P7

T

0.41

6.0E-06

1.11

1.03

0.94–1.13

0.53

rs4444235

14

53944201

RPS3AP46 - MIR5580

C

0.43

8.0E-10

1.11

1.03

0.94–1.13

0.51

rs9929218

16

68787043

CDH1

G

0.46

1.0E-08

1.10

1.13

1.01–1.25

0.03

rs4939827

18

48927093

SMAD7

T

0.27

8.0E-28

1.20

1.22

1.11–1.34

0.03

rs10411210

19

33041394

RHPN2

C

0.31

5.0E-09

1.15

1.01

0.88–1.16

0.92

rs4925386

20

62345988

LAMA5

C

0.58

2.0E-10

1.08

1.08

0.98–1.19

0.14

rs961253

20

6423634

FGFR3P3 - CASC20

A

0.28

2.0E-10

1.12

1.10

1.00–1.22

0.05

rs5934683

X

9783434

GPR143 - SHROOM2

C

0.57

7.0E-10

1.07

1.04

0.93–1.17

0.46

  1. SNPs associated with CRC risk in MCC population with p < 0.05 are highlighted in bold.
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