Table 1 baseline characteristics.

From: Optical coherence tomography evaluation of pulmonary arterial vasculopathy in Systemic Sclerosis

 

PAH (n = 17)

Non-PAH (n = 5)

Age, years

62 +/− 12

62 +/− 5

Sex, females

13

4

LcSSC

15

5

NT-pro BNP, pmol/l Mean; Median; IQR

127, 30, 119

17, 15, 13

mPAP (mmHg); PVR (WU)

39 +/− 12; 5.8 +/− 2.3

18 +/− 1; 1.7 +/− 0.4

RAP; PAWP (mmHg)

7.1 +/− 3.5; 9.7+/− 2.4

5 +/− 1.4; 10.5 +/− 0.9

CO (l/min)

5 +/− 1

4.7 +/− 1.4

Targeted treatment Single/double/no therapy

11/5/1*

n.a.

Time from onset of SSC months

128 +/− 83

130 +/− 102

  1. CO (cardiac output), LcSSc (limited cutaneous systemic sclerosis), mPAP (mean pulmonary artery pressure), mPVR (mean pulmonary vascular resistance, PAH (pulmonary arterial hypertension), PAWP (pulmonary artery wedge pressure), RAP (right atrial pressure), SSc (systemic sclerosis), WU (wood unit).
  2. *Among 11 patients with single targeted therapy 7 patients received Phosphodiesterase-5 inhibitors and 4 patients received Endothelin receptor antagonists. The remaining 5 patients were on combination therapy with a Phosphodiesterase-5 inhibitor and an Endothelin receptor antagonist.