Figure 3: P. aeruginosa biofilms associated to 3-D lung epithelial cells could not be eradicated with high concentrations of antibiotics. | Scientific Reports

Figure 3: P. aeruginosa biofilms associated to 3-D lung epithelial cells could not be eradicated with high concentrations of antibiotics.

From: Antimicrobial efficacy against Pseudomonas aeruginosa biofilm formation in a three-dimensional lung epithelial model and the influence of fetal bovine serum

Figure 3

P. aeruginosa biofilms formed after 6 h on plastic or 3-D lung epithelial cells were exposed to high concentrations of gentamicin (50 μg/mL = 3x MIC, 500 μg/mL = 31x MIC), amikacin (50 μg/mL = 6x MIC, 500 μg/mL = 60x MIC) and colistin (50 μg/mL = 12.5x MIC) for an additional 17–18 h to assess their susceptibility to antibiotics. Control biofilms on plastic and 3-D cells were incubated for the same duration without antibiotics. Gm = Gentamicin, Col = colistin, Am = amikacin. NS = non-significant (p > 0.05).

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