Table 1 Correlations between relapse rate and clinical variables.

From: Antithymocyte globulin improves the survival of patients with myelodysplastic syndrome undergoing HLA-matched unrelated donor and haplo-identical donor transplants

Variables

Not relapse No. (%)

Relapse No. (%)

χ2

P-value

BM blast (n = 85)

  

3.85

0.050

<5%

36 (90.0)

4 (10.0)

  

≥5%

33 (73.3)

12 (26.7)

  

WHO classification (n = 85)

  

3.31

0.191

RCUD/RCMD/MDS-U

34 (89.5)

4 (10.5)

  

RAEB-1

17 (77.3)

5 (22.7)

  

RAEB-2

18 (72.0)

7 (28.0)

  

IPSS (n = 84)

  

2.73

0.098

Low/Int-1

41 (87.2)

6 (12.8)

  

Int-2/High

27 (73.0)

10 (27.0)

  

Karyotype (n = 84)

  

11.19

0.004

Good

43 (91.5)

4 (8.5)

 

Int

17 (60.7)

11 (39.3)

  

Poor

8 (88.9)

1 (11.1)

  

Secondary MDS (n = 85)

  

1.01

0.449

Yes

11 (91.7)

1 (8.3)

  

No

58 (79.5)

15 (20.5)

  

Progression pre-HSCT(n = 85)

  

8.02

0.005

Yes

9 (56.2)

7 (43.8)

  

No

60 (87.0)

9 (13.0)

  

Donor type (n = 85)

  

0.07

0.932

MSD

31 (81.6)

7 (18.4)

  

Non-MSD

38 (80.9)

9 (19.1)

  

Conditioning (n = 85)

  

0.47

0.491

MAC

64 (82.1)

14 (17.9)

  

RIC

5 (71.4)

2 (28.6)

  

ATG (n = 85)

  

0.036

0.849

Yes

32 (82.1)

7 (17.9)

 

No

37 (80.4)

9 (19.6)

  

Therapies pre-HSCT (n = 85)

  

2.60

0.107

DAC ± chemotherapy

32 (74.4)

11 (25.6)

  

BSC

37 (88.1)

5 (11.9)

  
  1. Secondary MDS: MDS that transformed from chronic aplastic anemia; Progression pre-HSCT: MDS that progressed to advanced stage or AML; MSD: matched sibling donors; Non-MSD: including matched unrelated donors (MUD) and haplo-identical donors (HID); MAC: myeloablative conditioning; RIC: reduced intensive conditioning; ATG: Rabbitantithymocyte globulin; DAC: decitabine; BSC: basic supportive care, including erythropoiesis-stimulating agent and blood transfusion.