Table 3 Univariate analysis of prognostic factors impacting OSPT and OS.
Variables | No. | Median-OSPT | P-value | Median-OS | P-value |
|---|---|---|---|---|---|
Gender (n = 85) | 0.438 | 0.374 | |||
Male | 53 | NA. | 48 | ||
Female | 32 | 57.2 | NA. | ||
Age (n = 85) | 0.056 | 0.047 | |||
<40years | 43 | NA. | NA. | ||
≥40years | 42 | 27.6 | 32.9 | ||
WBC (n = 85) | 0.774 | 0.691 | |||
<4*10E9/L | 72 | 57.2 | 60.2 | ||
≥4*10E9/L | 13 | NA. | NA. | ||
HB (n = 85) | 0.545 | 0.566 | |||
<100 g/L | 70 | 57.2 | 59.1 | ||
≥100 g/L | 15 | 40.1 | 60.2 | ||
PLT (n = 85) | 0.701 | 0.781 | |||
<50*10E9/L | 54 | NA. | NA. | ||
≥50*10E9/L | 31 | 57.2 | 60.2 | ||
BM blast (n = 85) | 0.809 | 0.954 | |||
<5% | 40 | 40.1 | 60.2 | ||
≥5% | 45 | 57.2 | NA. | ||
WHO classification(n = 85) | 0.554 | 0.582 | |||
RCUD/RCMD/MDS-U | 38 | 40.1 | 60.2 | ||
RAEB-1 | 22 | NA. | NA. | ||
RAEB-2 | 25 | 57.2 | 59.1 | ||
IPSS (n = 84) | 0.632 | 0.880 | |||
Low/Int-1 | 47 | 40.1 | 60.2 | ||
Int-2/High | 37 | NA. | 59.1 | ||
Karyotype (n = 84) | 0.918 | 0.965 | |||
Good | 47 | 57.2 | NA. | ||
Int | 28 | 40.1 | 48.0 | ||
Poor | 9 | NA. | NA. | ||
Conditioning (n = 85) | 0.056 | 0.043 | |||
MAC | 78 | NA. | NA. | ||
RIC | 7 | 8.17 | 11.2 | ||
Stem cell source (n = 85) | 0.004 | 0.004 | |||
Marrow | 17 | 22.9 | 23.2 | ||
PBSCs | 43 | NA. | NA. | ||
Marrow + PBSCs | 24 | 57.2 | 59.1 | ||
Cord | 1 | 0.4 | 4.73 | ||
Therapies pre-HSCT(n = 85) | 0.843 | 0.902 | |||
DAC ± chemotherapy | 43 | 57.2 | 60.2 | ||
BSC | 42 | NA. | NA. | ||
CR Pre-HSCT(n = 85) | 0.249 | 0.290 | |||
Yes | 13 | NA. | NA. | ||
No | 72 | 40.1 | 60.2 | ||
Secondary MDS (n = 85) | 0.525 | 0.563 | |||
Yes | 12 | 16.1 | 33.4 | ||
No | 73 | 57.2 | 60.2 | ||
ATG (n = 85) | 0.025 | 0.016 | |||
Yes | 39 | NA. | NA. | ||
No | 46 | 22.9 | 27.2 | ||
Progressionpre-HSCT (n = 85) | 0.506 | 0.520 | |||
Yes | 16 | 19.0 | 22.7 | ||
No | 69 | 57.2 | 60.2 | ||
Donor type (n = 85) | 0.001 | 0.001 | |||
MSDs | 38 | 22.9 | 27.2 | ||
MUDs | 29 | NA. | NA. | ||
HIDs | 18 | NA. | NA. | ||
Infection (n = 78) | 0.053 | 0.094 | |||
Yes | 52 | 27.6 | 33.5 | ||
No | 26 | 57.2 | NA. | ||
aGVHD (n = 78) | 0.795 | 0.877 | |||
Yes | 43 | 57.2 | 59.1 | ||
No | 35 | NA. | NA. | ||
aGVHD (n = 78) | 0.524 | 0.631 | |||
No | 35 | NA. | NA. | ||
I-II | 25 | NA. | NA. | ||
III-IV | 18 | 19.0 | 27.2 | ||
cGVHD (n = 67) | 0.069 | 0.075 | |||
Yes | 35 | 57.2 | 59.1 | ||
No | 32 | NA. | NA. | ||
HC (n = 78) | 0.922 | 0.720 | |||
Yes | 20 | NA. | 48.0 | ||
No | 58 | 57.2 | 59.1 | ||
EBV (n = 78) | 0.013 | 0.013 | |||
Yes | 16 | NA. | NA. | ||
No | 62 | 27.6 | 33.4 | ||
CMV (n = 78) | 0.232 | 0.212 | |||
Yes | 28 | NA. | NA. | ||
No | 50 | 31.1 | 48.0 |
