Figure 5: XMJ prevents endothelial dysfunction in aortic arteries isolated from rats ex vivo. | Scientific Reports

Figure 5: XMJ prevents endothelial dysfunction in aortic arteries isolated from rats ex vivo.

From: Traditional Chinese medicine xin-mai-jia recouples endothelial nitric oxide synthase to prevent atherosclerosis in vivo

Figure 5

The isolated rat aortic rings were incubated with XMJ (25, 50, 100 μg/ml) for 30 minutes followed by exposure to H2O2 (0.2 mM) for 6 hours. (A) NO levels and (B) MDA levels in aortic tissues were assessed, respectively. (C) The endothelium-dependent relaxation induced by acetylcholine (Ach) and (D) endothelium-independent relaxation elicited by sodium nitroprusside (SNP) were assayed in organ chamber. All data were expressed as mean ± SEM. N is 5 in each group. *P < 0.05 VS Control, #P < 0.05 VS H2O2 alone.

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